G. B. Moroz, E. V. Fominskiy, А. N. Shilova, V. А. Shmyrev, V. V. Lomivorotov, E. N. Meshalkin Research Institute of Blood Circulation Pathology, Novosibirsk, RF
D. G. Shakhin, St. Petersburg Mutli-Purpose Center, St. Petersburg, RF
The article describes the impact of the targeted therapy with colloid and crystalloid infusion solutions on renal function and fluid balance during the surgery and early post-surgery period in the patients who underwent aortocoronary bypass under cardio-pulmonary bypass. No differences have been found in the frequency of acute renal lesion as per AKI and the need in the substitution renal therapy. During one stage of the study the lower rates of urine neutrophil gelatinase-associated lipocalin have been observed in the group of crystalloids. The lack of confident differences in the clinical course of the post-surgery period makes the use of the balanced crystalloid solution more preferable compared to colloid solutions.
Key words: infusion therapy, targeted therapy, acute renal lesion, NGAL, fluid balance, cardiac surgery.
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